人造器官工程课程详细信息

课程号 00333128 学分 3
英文名称 Artificial Organ Engineering
先修课程
中文简介 人造器官对人类生活的影响正变得势不可挡,全球范围内,每年约有2500万人的生活因此得到改善。目前,人造器官最广为接受的定义是通过工程技术设计与制造的组织、器官或设备。为实现特定功能,人造器官被植入或集成入人体,而接受者也因此能回归或改善日常生活。人造器官的应用包括以下方面:提升人的生活自理能力(如假肢),恢复与社会正常互动的能力(如眼镜),改善体貌特征(如癌症手术后的整形修复),提供生命维持(如器官移植等待期中的维生系统),提升个体竞争力和生存能力(如机械外骨骼)等等。课程目标包含三个方面:区分人造器官目前多样的制造技术与工艺;描述人造心脏瓣膜、人工心脏、心脏辅助装置、起搏器、人工肾和神经假体的功能;探讨人造器官的设计要素,包括对人工肾与人工肺基本数学模型的讨论。
英文简介 The impact of artificial organs on human life is overwhelming! Every year, they affect the lives of some 25 million people worldwide. The commonly accepted definition of an artificial organ is that of an engineered tissue, organ or device. It is implanted into or integrated with a living body for a specific function to enable the recipient a return to a normal or enhanced life, or to continue living on either a temporary or permanent basis. Examples of artificial organs being deployed include enhancing a person’s ability for selfcare (artificial limb), interacting normally with society (glasses – yes, these too), improving physical appearance (cosmetic restoration after cancer surgery), providing life-support (awaiting transplant), increasing competitiveness and/or survivability (exoskeleton), etc. The aims of the course are three folds: distinguish various and current state-of-art technologies for artificial organs, describe the functions of artificial heart valves, artificial heart, cardiac assist devices, pacemaker, artificial kidney and neuroprothesis and discuss design considerations of bio artificial organs that includes a fundamental mathematical modeling of artificial kidney and artificial lung.
开课院系 工学院
通选课领域  
是否属于艺术与美育
平台课性质  
平台课类型  
授课语言 英文
教材 The Biomedical Engineering Handbook – Tissue Engineering & Artificial Organs,Bronzino, J. D.,Taylor & Francis.,2006;
Design of Artificial Human Joints & Organs,Subrata Pal,Springer Publishers,2014;
参考书
教学大纲 Students will be exposed to current state-of-art technologies for artificial organs. They will learn the varying functions of artificial heart and valves, cardiac devices, pacemaker, artificial kidney and artificial heart. They will also learn the design considerations that include a fundamental mathematical modelling of artificial kidney and artificial lung.
Synopsis
The impact of artificial organs on human life is overwhelming! Every year, they affect the lives of some 25 million people worldwide. The commonly accepted definition of an artificial organ is that of an engineered tissue, organ or device. It is implanted into or integrated with a living body for a specific function to enable the recipient a return to a normal or enhanced life, or to continue living on either a temporary or permanent basis. Examples of artificial organs being deployed include enhancing a person’s ability for selfcare (artificial limb), interacting normally with society (glasses – yes, these too), improving physical appearance (cosmetic restoration after cancer surgery), providing life-support (awaiting transplant), increasing competitiveness and/or survivability (exoskeleton), etc. The aims of the course are three folds: distinguish various and current state-of-art technologies for artificial organs, describe the functions of artificial heart valves, artificial heart, cardiac assist devices, pacemaker, artificial kidney and artificial heart,
neuroprothesis and discuss design considerations of bio artificial organs that includes a fundamental mathematical modeling of artificial kidney and artificial lung.

Topics
1. Introduction to artificial organs engineering
2. Basic function of a kidney – principles of haemodialysis
3. Performance of mass transfer in artificial kidney
4. Operation of dialysis device through kinetic modelling of urea
5. Basic function of the lung – principles of cardiopulmonary diversion
6. Transportation of gases in blood
7. Design of artificial lung – membrane oxygenator
8. Implantable membrane oxygenator
9. Basic function of the heart – design of artificial heart valves
10. Prosthetic heart valves
11. Evaluation of prosthetic heart valves
12. Heart assist technology
13. Neuroprothesis
课堂讲授 60%
课堂报告、课堂讨论 40%
Homework Assignments 20%
Project Assignment
Interim Project Assessment (10%)
Final Project Assessment (10%)
20%
Midterm Exam 20%
Final Exam 40%
Total 100%
教学评估 Lee Poh Foong:
学年度学期:17-18-3,课程班:人造器官工程1,课程推荐得分:null,教师推荐得分:null,课程得分分数段:80及以下;
学年度学期:18-19-3,课程班:人造器官工程1,课程推荐得分:null,教师推荐得分:null,课程得分分数段:80及以下;